A clinical patho‐anatomical study of clinically silent multiple sclerosis
@article{Engell1989ACP, title={A clinical patho‐anatomical study of clinically silent multiple sclerosis}, author={Tine Engell}, journal={Acta Neurologica Scandinavica}, year={1989}, volume={79} }
ABSTRACT— This is the first study on the frequency, size, number, and location of plaques in clinically silent MS. Among the present 18 patients in whom MS was unexpectedly diagnosed at autopsy, it had been clinically silent in 13. An estimate of the prevalence of silent MS is about 25% of that diagnosed in vivo. In the silent group, the MS plaques were located mainly in the periventricular areas, and this may explain the silent nature of the disease.
110 Citations
[Radiologically isolated syndrome - MRI criteria and management tactic].
- Medicine, PsychologyZhurnal nevrologii i psikhiatrii imeni S.S. Korsakova
- 2016
Brain MRI findings in patients with asymptomatic lesions in the white matter can be interpreted as demyelinating lesions in some cases, but in the absence of clinical symptoms characteristic of multiple sclerosis, a diagnosis of MS cannot be made in the patients with these incidental findings.
Unsuspected (clinically silent) multiple sclerosis
- Medicine, PsychologyInternational Journal of Legal Medicine
- 2005
The incidental retrieval of a few, well-circumscribed, chronic multiple sclerosis plaques in a 49-year-old female who died from myocardial infarct is reported and methodological issues concerning in vivo and postmortem diagnosis of multiple sclerosis and their impact on the epidemiology of this disease are discussed.
‘Subclinical MS’: follow‐up of four cases
- Medicine, PsychologyEuropean journal of neurology
- 2008
Four cases of S‐MS cases followed‐up with clinical and MR examinations are described, finding characteristic lesions at magnetic resonance (MR) or at autopsy, in the absence of clinical evidence consistent with MS.
Radiologically Isolated Syndrome: An Overview
- Medicine, Psychology
- 2013
A definite diagnosis of multiple sclerosis cannot be made in patients with these incidental white matter lesions found on brain MRI, so these patients are now diagnosed as radiologically isolated syndrome (RIS).
Anomalies Characteristic of Central Nervous System Demyelination: Radiologically Isolated Syndrome.
- Medicine, PsychologyNeurologic clinics
- 2018
Radiologically Isolated Syndrome
- Medicine
- 2017
The features of pediatric radiologically isolated syndrome are discussed and an investigational and follow-up algorithm is proposed that aims to improve the quality of life of children diagnosed with multiple sclerosis.
Radiologically Isolated Syndrome: MR Imaging Features Suggestive of Multiple Sclerosis Prior to First Symptom Onset.
- MedicineNeuroimaging clinics of North America
- 2017
The Radiologically Isolated Syndrome: Look (Again) Before You Treat
- Medicine, PsychologyCurrent neurology and neuroscience reports
- 2011
What is and is not known about the long-term outcomes of RIS are highlighted and recommendations for clinicians when faced with this challenging situation are presented.
Radiologically isolated syndrome and multiple sclerosis.
- Medicine, PsychologyMultiple sclerosis and related disorders
- 2017
References
SHOWING 1-10 OF 10 REFERENCES
Silent brain lesions in patients with isolated idiopathic optic neuritis. A clinical and nuclear magnetic resonance imaging study.
- Medicine, PsychologyArchives of neurology
- 1986
Eight of 16 patients with isolated idiopathic optic neuritis were found to have one to several brain lesions by nuclear magnetic resonance scanning, which may be the only manifestation of a multicentric disease process that is disseminated in the central nervous system in the majority of cases.
A clinico‐pathoanatomical study of multiple sclerosis diagnosis
- Medicine, PsychologyActa neurologica Scandinavica
- 1988
Neuropathological examination of 518 consecutive patients with clinically definite MS revealed a correct diagnosis in 485 cases (94%).
Unsuspected multiple sclerosis.
- Medicine, PsychologyArchives of neurology
- 1983
Five patients known to have various medical problems were found unexpectedly at autopsy to have typical multiple sclerosis plaques. These were most often small and in a periventricular distribution…
Forms of benign multiple sclerosis. Report of two "clinically silent" cases discovered at autopsy.
- Medicine, PsychologyArchives of neurology
- 1967
A wide clinical experience with this exceedingly pleomorphic disease strongly suggests that it may on occasion be a mild disorder indeed—mild in its onset, in its pattern of evolution, or in its ultimate results.
INCIDENCE OF INFARCTS OF THE BRAIN IN HEART DISEASES.
- MedicineThe Journal of pathology and bacteriology
- 1964
Silent brain lesions in patients with isolated optic neuritis
- Arch Neurol
- 1986
Lyon-Caen 0. Les sclerosis en plaques asymptomatiques
- Rev Neurol
- 1981
Les sclerosis en plaques asymptomatiques
- Rev Neurol
- 1981
A clinico - pathoanatomical study of the diagnosis multiple sclerosis
- Acta Neurol Scand
- 1988