A clinical investigation of piritramide in the treatment of postoperative pain.

@article{Kay1971ACI,
  title={A clinical investigation of piritramide in the treatment of postoperative pain.},
  author={Brian Kay},
  journal={British journal of anaesthesia},
  year={1971},
  volume={43 12},
  pages={
          1167-71
        }
}
  • B. Kay
  • Published 1971
  • Medicine
  • British journal of anaesthesia
SUMMARY In a double-blind trial three dosage strengths of piritramide, 5, 10 and 20 mg, were compared with morphine 15 mg in the treatment of postoperative pain. Pain intensity was assessed by the patient, and pain relief and side effects by a nurse-assessor. A iog-dose response relationship was established for piritramide. Piritramide 20 mg was shown to be equivalent to morphine 15 mg in analgesic effect. From this and previous studies of piritramide, it appears that piritramide has a greater… Expand
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TLDR
Opioid-induced emesis was observed in about one-third of the patients using morphine and piritramide by patient-controlled analgesia (PCA) for PCA and the incidence of vomiting was one-half of that and potential differences in the occurrence of vomiting during PCA therapy between these micro-opioid receptor agonists can be excluded. Expand
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  • B. Kay
  • Medicine
  • British journal of anaesthesia
  • 1973
TLDR
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TLDR
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