A clinical comparison of sumatriptan nasal spray and dihydroergotamine nasal spray in the acute treatment of migraine.

@article{Boureau2000ACC,
  title={A clinical comparison of sumatriptan nasal spray and dihydroergotamine nasal spray in the acute treatment of migraine.},
  author={François Boureau and Ludwig Kappos and Jean Schoenen and P Esperança and E. Ashford},
  journal={International journal of clinical practice},
  year={2000},
  volume={54 5},
  pages={281-6}
}
A multinational, multicentre, randomised, double-blind, double-dummy, crossover study (368 patients treating two attacks) was conducted to compare the efficacy and tolerability of sumatriptan nasal spray (20 mg) with dihydroergotamine (DHE) nasal spray (1 mg plus optional 1 mg). At the primary efficacy time point of 60 minutes after dosing, significantly more patients obtained headache relief (change from moderate or severe to none or mild) after treatment with sumatriptan than with DHE (53… CONTINUE READING
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