A clinical assessment of the efficacy of a stannous-containing sodium fluoride dentifrice on dentinal hypersensitivity.

@article{Day2010ACA,
  title={A clinical assessment of the efficacy of a stannous-containing sodium fluoride dentifrice on dentinal hypersensitivity.},
  author={Trevor Day and Johannes Einwag and Joachim S. Hermann and Tao He and Mary Kay Anastasia and Matthew L. Barker and Yuqing Zhang},
  journal={The journal of contemporary dental practice},
  year={2010},
  volume={11 1},
  pages={
          E001-8
        }
}
AIM To measure the desensitizing benefits of an experimental stannous-containing sodium fluoride dentifrice versus a regular sodium fluoride negative control. METHODS AND MATERIALS This study was a randomized, double-blind, parallel group, four-week clinical trial. Subjects reporting dentinal hypersensitivity were enrolled and randomized to the experimental dentifrice or the control dentifrice to use twice daily for four weeks. Efficacy assessments (Air Blast) were performed at baseline and… 
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TLDR
In the present study, 107 patients went through a clinical examination and a survey to determine the prevalence of dental hypersensitivity, resulting in 65.4 percent, corresponding to 70 patients who experimented the symptom, among which 38 were women (71.7 percent) and 32 men (32 percent).
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References

SHOWING 1-10 OF 23 REFERENCES
The desensitizing efficacy of a novel stannous-containing sodium fluoride dentifrice: an 8-week randomized and controlled clinical trial.
TLDR
Both the experimental stannous-containing and positive control dentifrices provided significant reductions in both tactile and thermal dentin hypersensitivity compared to baseline at both Weeks 4 and 8.
A randomized clinical trial of the desensitizing efficacy of three dentifrices.
  • T. Schiff, Y. Zhang, H. Proskin
  • Medicine
    Compendium of continuing education in dentistry. (Jamesburg, N.J. : 1995). Supplement
  • 2000
TLDR
After 4- and 8-weeks' use of their assigned products, participants in the new dentifrice group demonstrated statistically significant improvements in tactile and air blast sensitivity, as compared to those using the positive and negative control dentifrices.
A new desensitizing dentifrice--an 8-week clinical investigation.
TLDR
The new dentifrice group demonstrated statistically significant improvements in tactile and thermal sensitivity over the two control groups, and was randomly assigned to each group with instructions to brush twice daily.
A randomized clinical study to assess the extrinsic staining profiles of stannous- and triclosan-containing dentifrices.
TLDR
Lobene stain composite mean scores were significantly lower in the two experimental stannous-containing dentifrice groups and the Colgate Total group when compared to Crest Gum Care, and all dentifrices were well-tolerated.
Comparative investigation of the desensitizing efficacy of a new dentifrice: a 14-day clinical study.
TLDR
It was concluded that a new dentif rice formulation containing 5.0% potassium nitrate and 0.454% stannous fluoride in a silica base provided a statistically significant reduction in dentinal hypersensitivity after only 10 days, as compared to a commercially available nondesensitizing control dentifrice.
The anti-plaque efficacy of a novel stannous-containing sodium fluoride dentifrice: a randomized and controlled clinical trial.
TLDR
Both the experimental and positive control dentifrices provided significantly lower mean whole mouth TMQHPI plaque scores after treatment compared to the negative control: 11.4% lower for the experimental stannous-containing dentifrice and 8.
Desensitizing efficacy of a new dentifrice containing 5.0% potassium nitrate and 0.454% stannous fluoride.
TLDR
The results of this examiner-blind clinical study support the conclusion that Colgate Sensitive Maximum Strength dentifrice provided superior levels of control of tactile and air blast sensitivity than did the clinically tested, commercially-available Sensodyne anti-hypersensitivity dentif Rice.
The effect of stannous fluoride on dentinal hypersensitivity.
TLDR
It was concluded that an effective strategy involving the use of stannous fluoride gel includes the application of the 0.717 per cent F solution in the office, effectively providing immediate relief, and that this solution requires approximately two to four weeks of continuous treatment to be effective.
Desensitizing efficacy of Colgate Sensitive Maximum Strength and Fresh Mint Sensodyne dentifrices.
TLDR
The results of this examiner-blind clinical study support the conclusion that the Colgate Sensitive Maximum Strength dentifrice containing 5.0% potassium nitrate and 0.454% stannous fluoride in a silica base provided superior levels of control of tactile and air blast sensitivity than the clinically tested, commercially-available anti-hypersensitivity dentif Rice.
The clinical performance of professionally dispensed bleaching gel with added amorphous calcium phosphate.
TLDR
This study demonstrates that ACP could be added to a 16 percent carbamide peroxide equivalent bleaching gel and result in a significant reduction of clinical measures of dentinal hypersensitivity, both during and after treatment.
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