A classical brown adipose tissue mRNA signature partly overlaps with brite in the supraclavicular region of adult humans.

@article{Jespersen2013ACB,
  title={A classical brown adipose tissue mRNA signature partly overlaps with brite in the supraclavicular region of adult humans.},
  author={Naja Zenius Jespersen and Therese Juhlin Larsen and Lone Peijs and S\oren Daugaard and Preben Hom\oe and Annika Loft and Jasper S de Jong and Neha Mathur and Barbara Cannon and Jan Nedergaard and Bente Klarlund Pedersen and Kirsten M\oller and Camilla C. Scheele},
  journal={Cell metabolism},
  year={2013},
  volume={17 5},
  pages={798-805}
}
Human brown adipose tissue (BAT) has been detected in adults but was recently suggested to be of brite/beige origin. We collected BAT from the supraclavicular region in 21 patients undergoing surgery for suspected cancer in the neck area and assessed the gene expression of established murine markers for brown, brite/beige, and white adipocytes. We demonstrate that a classical brown expression signature, including upregulation of miR-206, miR-133b, LHX8, and ZIC1 and downregulation of HOXC8 and… CONTINUE READING
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