A cis-Regulatory Signature in Ascidians and Flies, Independent of Transcription Factor Binding Sites

@article{Khoueiry2010ACS,
  title={A cis-Regulatory Signature in Ascidians and Flies, Independent of Transcription Factor Binding Sites},
  author={Pierre Khoueiry and Ute Rothb{\"a}cher and Yukio Ohtsuka and Fabrice Daian and Eric Frangulian and Agn{\`e}s Roure and Inna Dubchak and Patrick Lemaire},
  journal={Current Biology},
  year={2010},
  volume={20},
  pages={792-802}
}
BACKGROUND Transcription initiation is controlled by cis-regulatory modules. Although these modules are usually made of clusters of short transcription factor binding sites, a small minority of such clusters in the genome have cis-regulatory activity. This paradox is currently unsolved. RESULTS To identify what discriminates active from inactive clusters… CONTINUE READING