A circadian clock entrained by melatonin is ticking in the rat fetal adrenal.

@article{TorresFarfan2011ACC,
  title={A circadian clock entrained by melatonin is ticking in the rat fetal adrenal.},
  author={Claudia Torres-Farfan and Natalia Andrea Mendez and Lorena Abarzua-Catalan and Nelson Vilches and Guillermo J. Valenzuela and Mar{\'i}a Ser{\'o}n-Ferr{\'e}},
  journal={Endocrinology},
  year={2011},
  volume={152 5},
  pages={1891-900}
}
The adrenal gland in the adult is a peripheral circadian clock involved in the coordination of energy intake and expenditure, required for adaptation to the external environment. During fetal life, a peripheral circadian clock is present in the nonhuman primate adrenal gland. Whether this extends to the fetal adrenal gland like the rat is unknown. Here we explored in vivo and in vitro whether the rat fetal adrenal is a peripheral circadian clock entrained by melatonin. We measured the 24-h… CONTINUE READING

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