A chromatin link to caste identity in the carpenter ant Camponotus floridanus.

@article{Simola2013ACL,
  title={A chromatin link to caste identity in the carpenter ant Camponotus floridanus.},
  author={Daniel F. Simola and Chaoyang Ye and Navdeep S. Mutti and Kelly Dolezal and Roberto Bonasio and J{\"u}rgen Liebig and Danny Reinberg and Shelley L. Berger},
  journal={Genome research},
  year={2013},
  volume={23 3},
  pages={
          486-96
        }
}
In many ant species, sibling larvae follow alternative ontogenetic trajectories that generate striking variation in morphology and behavior among adults. These organism-level outcomes are often determined by environmental rather than genetic factors. Therefore, epigenetic mechanisms may mediate the expression of adult polyphenisms. We produced the first genome-wide maps of chromatin structure in a eusocial insect and found that gene-proximal changes in histone modifications, notably H3K27… 
Epigenetic Mechanisms Governing Behavioral Reprogramming in the Ant Camponotus floridanus
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The results suggest REST/CoREST mediated repression of JHe may be a significant source of stable changes to foraging in behaviorally reprogrammed Majors, indicating a critical period, or ‘window’ of epigenetic sensitivity to HDACi exists in young majors.
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It is found that different transcription factors and functionally distinct sets of genes are recruited during larval development to induce the four alternative trajectories of sphingolipid metabolism, a conserved molecular pathway involved in development, obesity, and aging.
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It is shown that at 96 h of larval growth, the queen-specific chromatin pattern is already established, whereas the worker determination is not, thus providing experimental support for the perceived timing of this critical point in developmental heterochrony in two types of honey bee females.
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Findings reveal the epigenome as a likely substrate underlying caste-based division of labor in eusocial insects as well as the conserved role of CBP in learning and memory in both invertebrates and mammals.
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These findings elucidate a pathway of transcription factor binding leading to a repressive epigenetic axis that lies at the crux of development and hormonal signaling to define worker caste identity in C. floridanus.
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It is found that many histone modifications are strongly predictive of DNA methylation levels in genes, and that these epigenetic signals are more predictive of gene expression when considered together than when considered independently.
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Using head samples from the leaf-cutting ant Acromyrmex echinatior, RNA editomes across eusocial castes are compared and the level of editing varies for the same site between castes, suggesting that RNA editing might be a general mechanism that shapes caste behaviour in ants.
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It is shown that the honeybee genome is structured with respect to plasticity; genes that respond to an environmental trigger are colocated in the honey bee genome in a series of gene clusters, many of which have been assembled in the last 80 My during the evolution of the Apidae.
Histone acetylation regulates the expression of genes involved in worker reproduction in the ant Temnothorax rugatulus
TLDR
The results suggest that histone acetylation is involved in the molecular regulation of worker reproduction, and point to an important role of histone modifications in modulating phenotypic plasticity of life history traits in social insects.
Chromatin accessibility and transcriptome landscapes of Monomorium pharaonis brain
TLDR
This study profiled the transcriptome and chromatin accessibility of brain tissues in three Monomorium pharaonis ant castes and identified specific genes and open chromatin regions in the genome that may be associated with the social function of these castes.
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References

SHOWING 1-10 OF 54 REFERENCES
Genomic Comparison of the Ants Camponotus floridanus and Harpegnathos saltator
TLDR
The genomes of two socially divergent ant species exhibiting differences in caste development are sequenced and used to compare gene expression and identify differences in epigenetic gene regulation that lead to the phenotypic differences.
DNA methylation is widespread and associated with differential gene expression in castes of the honeybee, Apis mellifera
TLDR
The results highlight the potential significance of epigenetic modifications, such as DNA methylation, in developmental processes in social insects and provide fertile ground for future studies of phenotypic plasticity and genomic imprinting.
The Gene vitellogenin Has Multiple Coordinating Effects on Social Organization
TLDR
It is shown by use of RNA interference that vitellogenin gene activity paces onset of foraging behavior, primes bees for specialized foraging tasks, and influences worker longevity, supporting the view that the worker specializations that characterize hymenopteran sociality evolved through co-option of reproductive regulatory pathways.
Functional Interaction between the CoactivatorDrosophila CREB-Binding Protein and ASH1, a Member of the Trithorax Group of Chromatin Modifiers
TLDR
The results thus implicate a second class of chromatin-associated proteins in mediating dCBP function and imply that dC BP might be involved in the regulation of higher-order chromatin structure.
Royalactin induces queen differentiation in honeybees
TLDR
It is shown that a 57-kDa protein in royal jelly, previously designated as royalactin, induces the differentiation of honeybee larvae into queens through an Egfr-mediated signalling pathway.
Trithorax and dCBP Acting in a Complex to Maintain Expression of a Homeotic Gene
Trithorax (Trx) is a member of the trithorax group (trxG) of epigenetic regulators, which is required to maintain active states of Hox gene expression during development. We have purified from
The Developmental Basis of Worker Caste Polymorphism in Ants
TLDR
In ants, the simplest developmental switch, revision of critical size alone, does not lead to discontinuous phenotypes, and only when changes in growth rules are tied to the decision to revise critical size are distinct phenotypes produced from the alternative developmental programs.
Reproductive protein protects functionally sterile honey bee workers from oxidative stress.
TLDR
The finding suggests that one mechanistic explanation for patterns of longevity in bees is that a reproductive regulatory pathway has been remodeled to extend life, and is of considerable relevance to research on longevity regulation that builds largely on inference from solitary model species.
Integrative epigenomic mapping defines four main chromatin states in Arabidopsis
TLDR
This first combinatorial view of the Arabidopsis epigenome points to simple principles of organization as in metazoans and provides a framework for further studies of chromatin‐based regulatory mechanisms in plants.
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