A chitosan-glutathione based injectable hydrogel for suppression of oxidative stress damage in cardiomyocytes.

@article{Li2013ACB,
  title={A chitosan-glutathione based injectable hydrogel for suppression of oxidative stress damage in cardiomyocytes.},
  author={Junjie Li and Yao Shu and Tong Hao and Yan Wang and Yufeng Qian and Cuimi Duan and Hongyu Sun and Qiuxia Lin and Changyong Wang},
  journal={Biomaterials},
  year={2013},
  volume={34 36},
  pages={9071-81}
}
Overproduction of reactive oxygen species (ROS) is closely associated with myocardial infarction. The oxidative stress damage caused by ROS in grafted cells and host cells presents a major obstacle for successful myocardial repairs in cardiac tissue engineering. Previous injectable biomaterials in use of myocardial repairs typically lack consideration of their antioxidant properties. In this work, a thermosensitive chitosan chloride-glutathione (CSCl-GSH) hydrogel was developed to suppress the… CONTINUE READING
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