A chimeric hemiterpene biosynthesis inMorus alba cell cultures

Morus alba L. callus and cell suspension cultures [1] produce chalcomoracin (CAL) [2], a phenolic constituent bearing two hemiterpene moieties. Administration of 13C-labeled acetate [3] and Omethylated chalcone derivatives [4] to the M. alba cell cultures revealed that CAL is biosynthesized through a stereospecific intermolecular Diels-Alder type reaction… CONTINUE READING