A chimera embryo assay reveals a decrease in embryonic cellular proliferation induced by sperm from X-irradiated male mice.

@article{Obasaju1989ACE,
  title={A chimera embryo assay reveals a decrease in embryonic cellular proliferation induced by sperm from X-irradiated male mice.},
  author={Michael Femi Obasaju and Lynn M. Wiley and D J Oudiz and Otto G. Raabe and James W. Overstreet},
  journal={Radiation research},
  year={1989},
  volume={118 2},
  pages={246-56}
}
Male mice were divided into three experimental groups and a control group. Mice in the experimental groups received one of three doses of acute X irradiation (1.73, 0.29, and 0.05 Gy) and together with the control unirradiated mice were then mated weekly to unirradiated female mice for a 9-week experimental period. Embryos were recovered from the weekly matings at the four-cell stage and examined by the chimera assay for proliferative disadvantage. Aggregation chimeras were constructed of… CONTINUE READING