A chemically synthesized peptide which elicits humoral and cellular immune responses to mycobacterial antigens.

Abstract

Monoclonal antibodies directed to Mycobacterium bovis BCG (BCG) and to M. tuberculosis H37Rv (H37Rv) were used in conjunction with affinity chromatography to prepare a mycobacterial component which was designated BCG-a. A synthetic peptide antigen was prepared based on the amino acid sequence of BCG-a and was designated BCG-a-P. Significant immunological… (More)

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Cite this paper

@article{Minden1986ACS, title={A chemically synthesized peptide which elicits humoral and cellular immune responses to mycobacterial antigens.}, author={Percy Minden and Richard A. Houghten and John R. Spear and Thomas M. Shinnick}, journal={Infection and immunity}, year={1986}, volume={53 3}, pages={560-4} }