A chemical biology approach reveals an opposite action between thermospermine and auxin in xylem development in Arabidopsis thaliana.

@article{Yoshimoto2012ACB,
  title={A chemical biology approach reveals an opposite action between thermospermine and auxin in xylem development in Arabidopsis thaliana.},
  author={Kaori Yoshimoto and Yoshiteru Noutoshi and Ken-Ichiro Hayashi and Ken Shirasu and Taku Takahashi and Hiroyasu Motose},
  journal={Plant & cell physiology},
  year={2012},
  volume={53 4},
  pages={635-45}
}
Thermospermine, a structural isomer of spermine, is produced through the action of ACAULIS5 (ACL5) and suppresses xylem differentiation in Arabidopsis thaliana. To elucidate the molecular basis of the function of thermospermine, we screened chemical libraries for compounds that can modulate xylem differentiation in the acl5 mutant, which is deficient in thermospermine and shows a severe dwarf phenotype associated with excessive proliferation of xylem vessels. We found that the isooctyl ester of… CONTINUE READING
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