Corpus ID: 5793491

A checklist for evaluating reports of expression profiling for treatment selection.

@article{Simon2006ACF,
  title={A checklist for evaluating reports of expression profiling for treatment selection.},
  author={R. Simon},
  journal={Clinical advances in hematology & oncology : H&O},
  year={2006},
  volume={4 3},
  pages={
          219-24
        }
}
  • R. Simon
  • Published 2006
  • Medicine
  • Clinical advances in hematology & oncology : H&O
Oncologists need improved tools for selecting the right treatment for a given patient because many patients do not benefit from administered therapies. The use of expression profiling of tumors has increased dramatically and many claims are made for the value of expression signatures in treatment selection. It is difficult, however, for oncologists to critically evaluate published results in this technology- and statistics-intensive field. A checklist is presented to help oncologists evaluate… Expand
10 Citations

Tables and Topics from this paper

Molecular signatures of thyroid follicular neoplasia.
  • 28
  • PDF
Molecular Diagnostics
  • 3
Laboratory-developed test--SynFRAME: an approach for assessing laboratory-developed tests synthesized from prior appraisal frameworks.
  • 14
  • Highly Influenced
  • PDF
Companion diagnostics at the intersection of personalized medicine and healthcare delivery.
  • 5
  • Highly Influenced
Assessing the Performance of Prediction Models: A Framework for Traditional and Novel Measures
  • 2,351
  • PDF

References

SHOWING 1-10 OF 35 REFERENCES
Roadmap for developing and validating therapeutically relevant genomic classifiers.
  • R. Simon
  • Medicine
  • Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • 2005
  • 383
  • PDF
Clinical trial designs for predictive marker validation in cancer treatment trials.
  • 472
On the efficiency of targeted clinical trials.
  • 183
  • PDF
2000 update of recommendations for the use of tumor markers in breast and colorectal cancer: clinical practice guidelines of the American Society of Clinical Oncology.
  • R. Bast, P. Ravdin, +7 authors M. Somerfield
  • Medicine
  • Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • 2001
  • 889
A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancer.
  • 5,107
  • PDF
...
1
2
3
4
...