A characterization of beta-adrenergic receptors on cellular and perigranular membranes of rat peritoneal mast cells.

@article{Donlon1982ACO,
  title={A characterization of beta-adrenergic receptors on cellular and perigranular membranes of rat peritoneal mast cells.},
  author={Mildred A. Donlon and Walter A. Hunt and George N. Catravas and Michael Kaliner},
  journal={Life sciences},
  year={1982},
  volume={31 5},
  pages={
          411-6
        }
}
Beta-adrenergic receptors were characterized by measuring the specific binding of 3H-dihydroalprenolol (DHA) on intact isolated rat peritoneal mast cells (RPMC) and on perigranular membranes derived from purified RPMC granules. The specific binding of 3H-DHA reaches an equilibrium within 30 min at 5 degrees C and is linear with cell number. Scatchard… CONTINUE READING