A characterization of DNA release in Pseudomonas aeruginosa cultures and biofilms

@article{AllesenHolm2006ACO,
  title={A characterization of DNA release in Pseudomonas aeruginosa cultures and biofilms},
  author={Marie Allesen-Holm and Kim Bundvig Barken and Liang Yang and Mikkel Klausen and Jeremy S Webb and Staffan Kjelleberg and S{\o}ren Molin and Michael Givskov and Tim Tolker-Nielsen},
  journal={Molecular Microbiology},
  year={2006},
  volume={59}
}
Pseudomonas aeruginosa produces extracellular DNA which functions as a cell‐to‐cell interconnecting matrix component in biofilms. Comparison of extracellular DNA and chromosomal DNA by the use of polymerase chain reaction and Southern analysis suggested that the extracellular DNA is similar to whole‐genome DNA. Evidence that the extracellular DNA in P. aeruginosa biofilms and cultures is generated via lysis of a subpopulation of the bacteria was obtained through experiments where extracellular… 
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