A change in the aggregation pathway of bovine serum albumin in the presence of arginine and its derivatives

@inproceedings{Borzova2017ACI,
  title={A change in the aggregation pathway of bovine serum albumin in the presence of arginine and its derivatives},
  author={Vera A. Borzova and Kira A. Markossian and Sergey Yu. Kleymenov and Boris I. Kurganov},
  booktitle={Scientific Reports},
  year={2017}
}
Chemical chaperones including arginine and its derivatives are widely used by biochemists working on the design of agents, which are able to efficiently suppress protein aggregation. To elucidate the mechanisms of anti-aggregation activity of chemical chaperones, methods based on registration of the increment in light scattering intensity must be supplemented with methods for direct detection of the portion of aggregated protein (γagg). For this purpose asymmetric flow field-flow fractionation… CONTINUE READING
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