A cerebrospinal fluid glucose biosensor for diabetes mellitus.

@article{Gilbert1992ACF,
  title={A cerebrospinal fluid glucose biosensor for diabetes mellitus.},
  author={Jan Wade Gilbert and Hal C. Weiser and Frank P. Holladay},
  journal={ASAIO journal},
  year={1992},
  volume={38 2},
  pages={
          82-7
        }
}
A cerebrospinal fluid (CSF) glucose biosensor is introduced. The biosensor is a polarimeter that measures the rotation of plane polarized light proportional to glucose concentration. Preliminary in vitro studies revealed a linear response with good sensitivity over a range of glucose solutions (0-400 mg/dl). Anesthetized, adult dogs underwent intravenous glucose loading, and these preliminary in vivo studies resulted in good correlation (r = 0.98) between CSF polarimeter readings and CSF… CONTINUE READING

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