A century of the phage: past, present and future

  title={A century of the phage: past, present and future},
  author={G. Salmond and P. C. Fineran},
  journal={Nature Reviews Microbiology},
  • G. Salmond, P. C. Fineran
  • Published 2015
  • Biology, Medicine
  • Nature Reviews Microbiology
  • Viruses that infect bacteria (bacteriophages; also known as phages) were discovered 100 years ago. Since then, phage research has transformed fundamental and translational biosciences. For example, phages were crucial in establishing the central dogma of molecular biology — information is sequentially passed from DNA to RNA to proteins — and they have been shown to have major roles in ecosystems, and help drive bacterial evolution and virulence. Furthermore, phage research has provided many… CONTINUE READING
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