A centrosome interactome provides insight into organelle assembly and reveals a non-duplication role for Plk4

@inproceedings{Galletta2016ACI,
  title={A centrosome interactome provides insight into organelle assembly and reveals a non-duplication role for Plk4},
  author={Brian J Galletta and Carey J. Fagerstrom and Todd A. Schoborg and Tiffany A McLamarrah and John M Ryniawec and Daniel W Buster and Kevin C Slep and Gregory C Rogers and Nasser M Rusan},
  booktitle={Nature communications},
  year={2016}
}
The centrosome is the major microtubule-organizing centre of many cells, best known for its role in mitotic spindle organization. How the proteins of the centrosome are accurately assembled to carry out its many functions remains poorly understood. The non-membrane-bound nature of the centrosome dictates that protein-protein interactions drive its assembly and functions. To investigate this massive macromolecular organelle, we generated a 'domain-level' centrosome interactome using direct… CONTINUE READING
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