A cellular protein, activating transcription factor, activates transcription of multiple E1A-inducible adenovirus early promoters.

@article{Lee1987ACP,
  title={A cellular protein, activating transcription factor, activates transcription of multiple E1A-inducible adenovirus early promoters.},
  author={Kevin A. W. Lee and T Y Hai and Lakshmi Sivaraman and B Thimmappaya and Helen C. Hurst and Nicholas C. Jones and Michael R. Green},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1987},
  volume={84 23},
  pages={8355-9}
}
We have examined the relationship between sequence-specific DNA-binding proteins that activate transcription of E1A-inducible adenovirus early promoters. Factors previously referred to as E4F1 and E2A-EF bind to the E4 and E2A promoters, respectively. We demonstrate here that E4F1 and E2A-EF have identical DNA-binding specificity. Moreover, E4F1 and E2A-EF both activate transcription of the E4 and E2A promoters in vitro. These findings demonstrate that E4F1 and E2A-EF are the same factor, which… CONTINUE READING

From This Paper

Topics from this paper.
31 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 31 extracted citations

Similar Papers

Loading similar papers…