A cellular mechanism for cortical associations: an organizing principle for the cerebral cortex

@article{Larkum2013ACM,
  title={A cellular mechanism for cortical associations: an organizing principle for the cerebral cortex},
  author={Matthew Evan Larkum},
  journal={Trends in Neurosciences},
  year={2013},
  volume={36},
  pages={141-151}
}
A basic feature of intelligent systems such as the cerebral cortex is the ability to freely associate aspects of perceived experience with an internal representation of the world and make predictions about the future. Here, a hypothesis is presented that the extraordinary performance of the cortex derives from an associative mechanism built in at the cellular level to the basic cortical neuronal unit: the pyramidal cell. The mechanism is robustly triggered by coincident input to opposite poles… CONTINUE READING

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