A cellular factor is required for transcription of vaccinia viral intermediate-stage genes.

@article{Rosales1994ACF,
  title={A cellular factor is required for transcription of vaccinia viral intermediate-stage genes.},
  author={Rency L. Rosales and Geoff Sutter and Bernard Moss},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1994},
  volume={91 9},
  pages={
          3794-8
        }
}
The cytoplasmic location of vaccinia virus replication and evidence that the multisubunit DNA-dependent RNA polymerase, early and late stage transcription factors, capping and methylating enzymes, and poly(A) polymerase are virus encoded raised the possibility that all of the proteins needed for viral mRNA synthesis are of viral origin. Previous studies showed that four components from infected cells, the viral RNA polymerase and capping enzyme and two factors called vaccinia virus intermediate… CONTINUE READING
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