A cell-type specific ganglioside of glomerular podocytes in rat kidney: an O-acetylated GD3.

@article{Reivinen1992ACS,
  title={A cell-type specific ganglioside of glomerular podocytes in rat kidney: an O-acetylated GD3.},
  author={Jukka Reivinen and Harry Holth{\"o}fer and Aaro Miettinen},
  journal={Kidney international},
  year={1992},
  volume={42 3},
  pages={624-31}
}
We recently described a monoclonal antibody (clone 27A) that detected a membrane antigen specific for glomerular podocytes in adult rat kidney. After binding in vivo, the antibodies induced rapid changes in the foot processes. Here we show that in other rat tissues the antigen is detectable only in cells of adrenal medulla, in some cells of neural or neural crest origin, and in 1 to 5% of the cells of a rat pheochromocytoma cell line PC-12. Attempts to isolate the antigen revealed that it is an… CONTINUE READING
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