A cell surface protein that binds avian hepatitis B virus particles.

@article{Kuroki1994ACS,
  title={A cell surface protein that binds avian hepatitis B virus particles.},
  author={Kimiko Kuroki and Robert Man-Kit Cheung and Patricia L. Marion and Donald E Ganem},
  journal={Journal of virology},
  year={1994},
  volume={68 4},
  pages={
          2091-6
        }
}
We have identified a 180-kDa cellular glycoprotein (gp180) that binds with high affinity to duck hepatitis B virus (DHBV) particles. The protein was detected by coprecipitating labeled duck hepatocyte proteins with virions or recombinant DHBV envelope proteins, using nonneutralizing monoclonal antibodies to the virion envelope. Binding of gp180 requires only the pre-S region of the viral large envelope protein, since recombinant fusion proteins bearing only this region efficiently coprecipitate… CONTINUE READING

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