A cell-microelectronic sensing technique for the screening of cytoprotective compounds.

@article{zsvri2010ACS,
  title={A cell-microelectronic sensing technique for the screening of cytoprotective compounds.},
  author={B{\'e}la {\'O}zsv{\'a}ri and L{\'a}szl{\'o} G. Pusk{\'a}s and Lajos Istv{\'a}n Nagy and Iv{\'a}n Kanizsai and M{\'a}ri{\'o} Gyuris and Ram{\'o}na Mad{\'a}csi and Lili{\'a}na Z. Feh{\'e}r and Domokos Ger{\"o} and Csaba Szab{\'o}},
  journal={International journal of molecular medicine},
  year={2010},
  volume={25 4},
  pages={525-30}
}
In recent years, a new cell-based high throughput paradigm has emerged, which seeks to identify novel, pharmacologically active cytoprotective compounds. The essence of this approach is to create experimental models of cell injury relevant for a particular disease by establishing in vitro cell-based models, followed by high-throughput testing of compounds that affect the cellular response in a desired manner. Prior approaches typically used simple end-point analyses. To assess the… CONTINUE READING