A category approach for reproductive effects of phthalates.

@article{Fabjan2006ACA,
  title={A category approach for reproductive effects of phthalates.},
  author={Evelin Fabjan and Etje M. Hulzebos and Wim C. Mennes and Aldert H. Piersma},
  journal={Critical reviews in toxicology},
  year={2006},
  volume={36 9},
  pages={
          695-726
        }
}
In regulatory toxicology, the experimental assessment of reproductive toxicity is one of the most costly endpoints to perform. Categorizing chemicals is an approach that can be used to reduce animal tests in risk assessments of chemicals, for example, via REACH (Registration, Evaluation, and Authorization of Chemicals). The category approach was tested for reproductive toxicity with a group of 10 ortho-phthalate esters, with different side chain lengths. Three ortho-phthalates were used for… CONTINUE READING
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