A catalogue of eukaryotic transcription factor types, their evolutionary origin, and species distribution.

@article{Weirauch2011ACO,
  title={A catalogue of eukaryotic transcription factor types, their evolutionary origin, and species distribution.},
  author={Matthew T. Weirauch and Timothy R. Hughes},
  journal={Sub-cellular biochemistry},
  year={2011},
  volume={52},
  pages={
          25-73
        }
}
Transcription factors (TFs) play key roles in the regulation of gene expression by binding in a sequence-specific manner to genomic DNA. In eukaryotes, DNA binding is achieved by a wide range of structural forms and motifs. TFs are typically classified by their DNA-binding domain (DBD) type. In this chapter, we catalogue and survey 91 different TF DBD types in metazoa, plants, fungi, and protists. We briefly discuss well-characterized TF families representing the major DBD superclasses. We also… CONTINUE READING
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