A catalogue of Bilaterian-specific genes – their function and expression profiles in early development

  title={A catalogue of Bilaterian-specific genes – their function and expression profiles in early development},
  author={Andrea Kraemer-Eis and Luca Ferretti and Philipp H. Schiffer and Peter Heger and Thomas Wiehe},
Bilateria constitute a monophyletic group of organisms comprising about 99% of all living animals. Since their initial radiation about 540Mya they have evolved a plethora of traits and body forms allowing them to conquer almost any habitat on earth. There are only few truly uniting and shared morphological features retained across the phylum. Unsurprisingly, also the genetic toolkit of bilateria is highly diverged. In the light of this divergence we investigated if a set of bilaterian-specific… Expand


Evolutionary conservation of the eumetazoan gene regulatory landscape.
The results suggest that complex gene regulation originated at least 600 million yr ago, predating the common ancestor of eumetazoans, and Surprisingly, the distribution and abundance of gene regulatory elements relative to these genes are shared between Nematostella and bilaterian model organisms. Expand
Early origin of the bilaterian developmental toolkit
  • D. Erwin
  • Biology, Medicine
  • Philosophical Transactions of the Royal Society B: Biological Sciences
  • 2009
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The Ctenophore Genome and the Evolutionary Origins of Neural Systems
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Acoel development supports a simple planula-like urbilaterian
  • A. Hejnol, M. Martindale
  • Biology, Medicine
  • Philosophical Transactions of the Royal Society B: Biological Sciences
  • 2008
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The cnidarian-bilaterian ancestor possessed at least 56 homeoboxes: evidence from the starlet sea anemone, Nematostella vectensis
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Acoel development indicates the independent evolution of the bilaterian mouth and anus
The hypothesis that the bilaterian mouth and anus evolved simultaneously from a common blastoporal opening is contradicted, and it is suggested that a through gut might have evolved independently in different animal lineages. Expand
Sea Anemone Genome Reveals Ancestral Eumetazoan Gene Repertoire and Genomic Organization
A comparative analysis of the draft genome of an emerging cnidarian model, the starlet sea anemone Nematostella vectensis, suggests that gene “inventions” along the lineage leading to animals were likely already well integrated with preexisting eukaryotic genes in the eumetazoan progenitor. Expand
A genomewide survey of bHLH transcription factors in the coral Acropora digitifera identifies three novel orthologous families, pearl, amber, and peridot
A nearly full set of 70 basic helix-loop-helix (bHLH) transcription factors in this organism is characterized, comparable to 68 bHLH genes in the sea anemone, Nematostella vectensis, and larger than those in most other invertebrate metazoans. Expand
The Amphimedon queenslandica genome and the evolution of animal complexity
Comparative analysis enabled by the sequencing of the sponge genome reveals genomic events linked to the origin and early evolution of animals, including the appearance, expansion and diversification of pan-metazoan transcription factor, signalling pathway and structural genes. Expand