A case series and immunophenotypic analysis of CK20-/CK7+ primary neuroendocrine carcinoma of the skin.

Abstract

BACKGROUND The diagnosis of Merkel cell carcinoma (MCC) can be rather challenging; therefore, the immunohistochemical profile is important in confirming the microscopic diagnosis. Characteristic of the neuroendocrine and epithelial differentiation of MCC, antibodies to cytokeratin (CK) 20, CK7, epithelial membrane antigen, and neuron-specific enolase among… (More)

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