A case of prolonged human parvovirus B19 DNA-emia associated with polyclonal B cell activation.

@article{Nobutoki1996ACO,
  title={A case of prolonged human parvovirus B19 DNA-emia associated with polyclonal B cell activation.},
  author={Tatsuro Nobutoki and Hidetsugu Hori and Masamune Higashigawa and Eiichi Azuma and Masaharu Sakurai and Tohru Yoshizumi and Tadasu Nunoue},
  journal={Acta paediatrica Japonica : Overseas edition},
  year={1996},
  volume={38 4},
  pages={348-51}
}
The current paper reports an 8 year old girl with arthralgia and polyclonal B cell activation induced by human parvovirus B19 infection (HPV B19). The infection was diagnosed by the presence of the virus genome in sera. The patient presented with transient arthritis in the wrist, ankle joint and neck and elevation of immunoglobulin IgM antibodies to HPV B19 and rubella, antibodies to Mycoplasma and antistreptolysin O but without the typical clinical features of erythema infectiosum. The… CONTINUE READING