A case of pheochromocytoma producing parathyroid hormone-related protein and presenting with hypercalcemia.

@article{Kimura1990ACO,
  title={A case of pheochromocytoma producing parathyroid hormone-related protein and presenting with hypercalcemia.},
  author={Satoshi Kensuke Kimura and Yasuharu Nishimura and Ken Yamaguchi and Koichi Nagasaki and Keiji Shimada and Hiroshi Uchida},
  journal={The Journal of clinical endocrinology and metabolism},
  year={1990},
  volume={70 6},
  pages={1559-63}
}
A 54-yr-old man with a left adrenal pheochromocytoma showed mild hypercalcemia and elevated nephrogenous cAMP. Serum levels of PTH and 1,25-dihydroxyvitamin D3 were not elevated. Postoperatively, serum calcium and nephrogenous cAMP declined to normal ranges. Pathologically, the tumor was a benign pheochromocytoma. The clinical findings resembled those of humoral hypercalcemia of malignancy (HHM), and PTH-related protein (PTHrP) immunoreactivity was detected in the tumor extract at a… CONTINUE READING

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