[A case of inflammatory breast cancer successfully treated with intra-arterial infusion of high-dose epirubicin].

Abstract

A 56-year-old female with extensive inflammatory breast cancer was treated with intra-arterial infusion chemotherapy using a high dose of epirubicin. One cycle consisted of epirubicin; 150 mg (day 1, 4, 7) and daily administration of tamoxifen; 40 mg. After completion of 2 cycles of the regimen, both the main tumor and the extensive inflammatory skin lesion completely disappeared (CR). Hair loss, gastrointestinal disorders and leukopenia (nadir; 1,600) were the side effects encountered, but all of them were reversible. These findings suggested that dose-escalation of epirubicin was effective, and that cases with extensive skin involvement were also candidates for this modality.

Cite this paper

@article{Takatsuka1991ACO, title={[A case of inflammatory breast cancer successfully treated with intra-arterial infusion of high-dose epirubicin].}, author={Yuichi Takatsuka and Junji Gofuku and Toshihide Katoh and Yukiyasu Okamura and Kazu Kobayakawa and Takashi Kawahara}, journal={Gan to kagaku ryoho. Cancer & chemotherapy}, year={1991}, volume={18 8}, pages={1363-6} }