A case of hepatosplenic gamma-delta T-cell lymphoma with a transient response to fludarabine and alemtuzumab.

@article{Mittal2006ACO,
  title={A case of hepatosplenic gamma-delta T-cell lymphoma with a transient response to fludarabine and alemtuzumab.},
  author={Sajjan Mittal and Benedict J Milner and Peter W. Johnston and Dominic J. Culligan},
  journal={European journal of haematology},
  year={2006},
  volume={76 6},
  pages={531-4}
}
Hepatosplenic gamma-delta T-cell lymphoma is a rare, usually fatal lymphoma and available literature on management is sparse. Allografting is probably the only curative option. We describe a further case with a dramatic, though transient response to Fludarabine and Alemtuzumab combination, following a failure of conventional chemotherapy. Given the dreadful prognosis with conventional chemotherapy, it is a regimen worth pursuing as a disease reduction strategy prior to allograft where… CONTINUE READING

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