A case of hemolysis in ABO-unmatched liver transplantation: use of washed group O red blood cells and steroids.

Abstract

Liver transplantation is the only curative therapy for patients with end-stage liver disease. The high success rate and the increasing demand for the transplantation sometimes calls for ABO-compatible but nonidentical blood group orthotopic liver transplantation (OLT), which affords the opportunity to the production of antibody to red blood cells. Hemolytic anemia usually occurs 1 to 2 weeks after transplantation. Although mild in most patients, it can be life-threatening. Until now, a few cases showing hemolytic anemia due to donor ABO antibody formation after ABO-nonidentical OLT have been reported. In the reported cases of hemolytic anemia, most ABO-nonidentical OLT cases were O-to-A, but few reports are available on this subject with O-to-B ABO-nonidentical OLT. Herein, we report the experience with hemolysis after ABO-nonidentical OLT in a group O donor into a group B recipient and the successful treatment with transfusion of washed group O red blood cells and 60 mg dose of prednisolone for 3 days.

Cite this paper

@article{Bae2005ACO, title={A case of hemolysis in ABO-unmatched liver transplantation: use of washed group O red blood cells and steroids.}, author={Si Hyun Bae and Jeong Won Jang and Min Soo Kim and Hyun Jong Oh and Jong Young Choi and Nam Ik Han and Seung Kew Yoon and Joon Yeol Han and Eun - Jee Oh and Dong Gu Kim}, journal={The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi}, year={2005}, volume={45 5}, pages={369-73} }