A case of endocarditis caused by the yeast Pichia fabianii with biofilm production and developed in vitro resistance to azoles in the course of antifungal treatment.

@article{Hamal2008ACO,
  title={A case of endocarditis caused by the yeast Pichia fabianii with biofilm production and developed in vitro resistance to azoles in the course of antifungal treatment.},
  author={P Hamal and Jiri Ostransky and Milo{\vs} Dendis and Radek Horv{\'a}th and Filip Rů{\vz}i{\vc}ka and Vladim{\'i}r Buchta and Marcela Vejsov{\'a} and Pavel {\vS}auer and Petr Hejnar and Vladislav Raclavsk{\'y}},
  journal={Medical mycology},
  year={2008},
  volume={46 6},
  pages={601-5}
}
Pichia fabianii, a yeast rarely causing human infections, was isolated from the blood of a patient with aortic valve endocarditis. The isolates were initially identified biochemically as Candida pelliculosa, but based on direct sequencing of the ITS2 region of rRNA, they were subsequently reidentified as P. fabianii. Antifungal therapy with fluconazole and later with voriconazole led to the development of resistant variants which had high MIC values to both antifungals. Strong biofilm formation… CONTINUE READING

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Fungemia caused by

  • S Hirasaki, T Ijichi, N Fujita
  • Mycoses
  • 2004

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