A case of dense deposit disease associated with a group A streptococcal infection without the involvement of C3NeF or complement factor H deficiency

@article{Suga2010ACO,
  title={A case of dense deposit disease associated with a group A streptococcal infection without the involvement of C3NeF or complement factor H deficiency},
  author={Kenichi Suga and Shuji Kondo and Sato Matsuura and Yukiko Kinoshita and E Kiyoshi Kitano and Michiyo Hatanaka and Hajime Kitamura and Yoshihiko Hidaka and Takashi Oda and Shoji Kagami},
  journal={Pediatric Nephrology},
  year={2010},
  volume={25},
  pages={1547-1550}
}
A 14-year-old girl presented with acute glomerulonephritis. Tests revealed hypocomplementemia and elevated Antistreptolysin-O titers, and renal biopsy revealed endocapillary and mesangial proliferative glomerulonephritis with double contours of the glomerular basement membrane (GBM). Despite methylprednisolone pulse therapy and the administration of oral prednisolone, overt proteinuria and hypocomplementemia persisted. A second renal biopsy 6 months later confirmed the initial diagnosis of… CONTINUE READING
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