A case-control study of wood dust exposure, mutagen sensitivity, and lung cancer risk.

  title={A case-control study of wood dust exposure, mutagen sensitivity, and lung cancer risk.},
  author={Xifeng Wu and George L. Delclos and John F. Annegers and Melissa L Bondy and Susan E. Honn and Beverley K. Henry and Tao C Hsu and Margaret R. Spitz},
  journal={Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology},
  volume={4 6},
The associations between lung cancer risk, mutagen sensitivity (a marker of cancer susceptibility), and a putative lung carcinogen, wood dust, were assessed in a hospital-based case-control study. There were 113 African -American and 67 Mexican-American cases with newly diagnosed, previously untreated lung cancer and 270 controls, frequency-matched on age, ethnicity, and sex. Mutagen sensitivity ( 1 chromatid break/cell after short-term bleomycin treatment) was associated with statistically… CONTINUE READING
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