A case-control study of dietary salt intake in pediatric-onset multiple sclerosis.

  title={A case-control study of dietary salt intake in pediatric-onset multiple sclerosis.},
  author={Jamie Currie McDonald and Jennifer S. Graves and Amy Waldman and Timothy E. Lotze and Teri L. Schreiner and Anita L Belman and Benjamin M. Greenberg and Bianca Weinstock-Guttman and Gregory S Aaen and Jan Mendelt Tillema and Janace Hart and Sabeen Lulu and Jayne M. Ness and Yolanda Harris and Jennifer P. Rubin and Meghan S. Candee and Lauren B. Krupp and Mark P. Gorman and Leslie A. Benson and Moses Rodriguez and Tanuja Chitnis and Soe Soe Mar and Lisa F. Barcellos and Barbara A. Laraia and John W. Rose and Shelly Roalstad and Timothy C. Simmons and T. Charles Casper and Emmanuelle L. Waubant},
  journal={Multiple sclerosis and related disorders},
BACKGROUND High salt intake may be associated with pro-inflammatory changes in the immune response, and increased clinical and MRI activity in adults with relapsing-remitting multiple sclerosis. OBJECTIVE We sought to determine if dietary salt intake is associated with pediatric-onset MS risk in a multicenter, case-control study. METHODS Pediatric-onset CIS/MS cases within four years of onset and controls less than 22 years old recruited from 14 pediatric-MS centers were studied. Dietary… CONTINUE READING
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