A case-control study of cryptorchidism and maternal hormone concentrations in early pregnancy.

@article{Key1996ACS,
  title={A case-control study of cryptorchidism and maternal hormone concentrations in early pregnancy.},
  author={Timothy J Key and Diana Bull and Pat Ansell and A. R. Brett and Gary M. Clark and John Walker Moore and Clair E.D. Chilvers and Malcolm C. Pike},
  journal={British Journal of Cancer},
  year={1996},
  volume={73},
  pages={698 - 701}
}
Serum samples taken between 6 and 20 weeks of gestation were obtained from 28 mothers who gave birth to cryptorchid sons (cases) and from 108 control mothers. In comparison with controls the cases had 10% higher geometric mean oestradiol (95% CI -13% to +39%: P=0.42) and 10% lower geometric mean testosterone (95% CI -27% to +10%: P=0.30). Among the samples collected between 6 and 14 weeks of gestation geometric mean concentrations of oestradiol and testosterone were 5% lower (95% CI -32% to +31… CONTINUE READING

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