Corpus ID: 19332875

A cartilage derived novel compound DDP (2,6-dimethyldifuro-8-pyrone): isolation, purification, and identification.

@article{Gahunia2002ACD,
  title={A cartilage derived novel compound DDP (2,6-dimethyldifuro-8-pyrone): isolation, purification, and identification.},
  author={H. Gahunia and A. Lough and R. Vieth and K. Pritzker},
  journal={The Journal of rheumatology},
  year={2002},
  volume={29 1},
  pages={
          147-53
        }
}
  • H. Gahunia, A. Lough, +1 author K. Pritzker
  • Published 2002
  • Medicine
  • The Journal of rheumatology
  • OBJECTIVE Fluorescent biomolecules within cartilage matrix can be used as specific markers of cartilage metabolism. While establishing the protocol to evaluate mature collagen crosslinks in articular cartilage (AC) associated with maturation, aging, and osteoarthritis, chromatographic analysis of the crosslinks also revealed an apparently novel fluorescent peak. Preliminary investigation of this compound (now abbreviated DDP) in various tissues from rabbits, calves, chickens, and humans showed… CONTINUE READING
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