A carrier for GABA uptake exists on noradrenaline nerve endings in selective rat brain areas but not on serotonin terminals

  title={A carrier for GABA uptake exists on noradrenaline nerve endings in selective rat brain areas but not on serotonin terminals},
  author={Giambattista Bonanno and Maurizio Raiteri},
  journal={Journal of Neural Transmission},
γ-Aminobutyric acid (GABA) increased in a concentration-dependent way (3–300ΜM) the basal release of tritium from rat cerebral cortex and hippocampus synaptosomes, prelabelled with3H-noradrenaline (3H-NA); however, GABA was ineffective on hypothalamic nerve endings. The effect displayed by low concentrations (<10ΜM) of GABA was largely bicuculline-sensitive. Muscimol mimicked GABA, while (−)baclofen was inactive. The releasing effects produced by concentrations of GABA higher than 10ΜM were… 
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