A cardiac troponin T epitope conserved across phyla.

  title={A cardiac troponin T epitope conserved across phyla.},
  author={Nadia N. Malouf and Dan McMahon and Annette E Oakeley and Peter A. V. Anderson},
  journal={The Journal of biological chemistry},
  volume={267 13},
Troponin T is a thin filament protein that is important in regulating striated muscle contraction. We have raised a monoclonal antibody against rabbit cardiac troponin T, monoclonal (mAb) 13-11, that recognizes its epitope in cardiac troponin T isoforms from fish, bird, and mammal but not from frog. The number of these isoforms expressed in cardiac muscle varies among species and during development. Cardiac troponin T isoforms were not found in adult skeletal muscle, while they were expressed… CONTINUE READING


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