A carbon dioxide avoidance behavior is integrated with responses to ambient oxygen and food in Caenorhabditis elegans.

@article{Bretscher2008ACD,
  title={A carbon dioxide avoidance behavior is integrated with responses to ambient oxygen and food in Caenorhabditis elegans.},
  author={Andrew Jonathan Bretscher and Karl Emanuel Busch and Mario de Bono},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2008},
  volume={105 23},
  pages={8044-9}
}
Homeostasis of internal carbon dioxide (CO2) and oxygen (O2) levels is fundamental to all animals. Here we examine the CO2 response of the nematode Caenorhabditis elegans. This species inhabits rotting material, which typically has a broad CO2 concentration range. We show that well fed C. elegans avoid CO2 levels above 0.5%. Animals can respond to both absolute CO2 concentrations and changes in CO2 levels within seconds. Responses to CO2 do not reflect avoidance of acid pH but appear to define… CONTINUE READING
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