A cannabinoid quinone inhibits angiogenesis by targeting vascular endothelial cells.

@article{Kogan2006ACQ,
  title={A cannabinoid quinone inhibits angiogenesis by targeting vascular endothelial cells.},
  author={Natalya M. Kogan and Cristina Bl{\'a}zquez and Luis {\'A}lvarez {\'A}lvarez and Ruth Gallily and Michael Schlesinger and Manuel Alejandro P{\'e}rez Guzm{\'a}n and Raphael Mechoulam},
  journal={Molecular pharmacology},
  year={2006},
  volume={70 1},
  pages={51-9}
}
Recent findings on the inhibition of angiogenesis and vascular endothelial cell proliferation by anthracycline antibiotics, which contain a quinone moiety, make this type of compound a very promising lead in cancer research/therapy. We have reported that a new cannabinoid anticancer quinone, cannabidiol hydroxyquinone (HU-331), is highly effective against tumor xenografts in nude mice. For evaluation of the antiangiogenic action of cannabinoid quinones, collagen-embedded rat aortic ring assay… CONTINUE READING
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