A cannabinoid 2 receptor agonist attenuates bone cancer-induced pain and bone loss.

@article{LozanoOndoua2010AC2,
  title={A cannabinoid 2 receptor agonist attenuates bone cancer-induced pain and bone loss.},
  author={Alysia N Lozano-Ondoua and Courtney Wright and Anna Vardanyan and Tamara I King and Tally Marie Largent-Milnes and Mark Nelson and Juan Miguel Jim{\'e}nez-Andrade and Patrick W Mantyh and Todd W. Vanderah},
  journal={Life sciences},
  year={2010},
  volume={86 17-18},
  pages={646-53}
}
AIMS Cannabinoid CB(2) agonists have been shown to alleviate behavioral signs of inflammatory and neuropathic pain in animal models. AM1241, a CB(2) agonist, does not demonstrate central nervous system side effects seen with CB(1) agonists such as hypothermia and catalepsy. Metastatic bone cancer causes severe pain in patients and is treated with analgesics… CONTINUE READING