A candidate gene identification strategy utilizing mouse to human big-data mining: “3R-tenet” in COPD genetic research

@inproceedings{Vishweswaraiah2018ACG,
  title={A candidate gene identification strategy utilizing mouse to human big-data mining: “3R-tenet” in COPD genetic research},
  author={Sangeetha Vishweswaraiah and Leema George and Natarajan Purushothaman and Koustav Ganguly},
  booktitle={Respiratory research},
  year={2018}
}
BACKGROUND Early life impairments leading to lower lung function by adulthood are considered as risk factors for chronic obstructive pulmonary disease (COPD). Recently, we compared the lung transcriptomic profile between two mouse strains with extreme total lung capacities to identify plausible pulmonary function determining genes using microarray analysis… CONTINUE READING