A cancer/testis antigen microarray to screen autoantibody biomarkers of non-small cell lung cancer.

Abstract

Cancer/testis antigens (CTAs) are highly immunogenic in many tumors, especially in non-small cell lung cancer (NSCLC). A low-density protein microarray, which consisted of 72 CTAs and six non-CTAs, was used to screen for lung cancer-related autoantibodies. The CTA panel of NY-ESO-1, XAGE-1, ADAM29 and MAGEC1, had sensitivity and specificity values of 33… (More)
DOI: 10.1016/j.canlet.2012.08.019

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