A calcium-activated nonselective cation conductance underlies the plateau potential in rat substantia nigra GABAergic neurons.

@article{Lee2007ACN,
  title={A calcium-activated nonselective cation conductance underlies the plateau potential in rat substantia nigra GABAergic neurons.},
  author={Christian Ryan Lee and James M Tepper},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2007},
  volume={27 24},
  pages={6531-41}
}
Plateau potentials can be elicited in nigral GABAergic neurons by injection of 500 ms depolarizing current pulses from hyperpolarized holding potentials in whole-cell recordings in vitro. In approximately one-third of these neurons, plateau potentials were observed under control conditions and could be elicited in the remaining neurons after blocking potassium conductances. Application of the L-type calcium channel agonist Bay K 8644 or activation of NMDA receptors enhanced plateau potentials… CONTINUE READING
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