A cDNA clone for the precursor of rat mitochondrial ornithine transcarbamylase: comparison of rat and human leader sequences and conservation of catalytic sites.

@article{Kraus1985ACC,
  title={A cDNA clone for the precursor of rat mitochondrial ornithine transcarbamylase: comparison of rat and human leader sequences and conservation of catalytic sites.},
  author={Jan P Kraus and Peter E. Hodges and Carey L. Williamson and Arthur L Horwich and Frantisek Kalousek and Kenneth R. Williams and Leon E. Rosenberg},
  journal={Nucleic acids research},
  year={1985},
  volume={13 3},
  pages={943-52}
}
We have cloned a DNA complementary to the messenger RNA encoding the precursor of ornithine transcarbamylase from rat liver. This complementary DNA contains the entire protein coding region of 1062 nucleotides and 86 nucleotides of 5'- and 298 nucleotides of 3'-untranslated sequences. The predicted amino acid sequence has been confirmed by extensive protein sequence data. The mature rat enzyme contains the same number of amino acid residues (322) as the human enzyme and their amino acid… CONTINUE READING